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To better understand the mechanistics involved in deamidation of protonated peptides containing Gln and Asn, we employ here infrared ion spectroscopy to resolve the structures of the product ions resulting from NH 3 -loss from the protonated dipeptides of AlaAsn (AN), AsnAla (NA), AlaGln (AQ), and GlnAla (QA)
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(PMC9024532) A randomized controlled trial confirmed this advantage directly: adding growth factor serum post-microneedling produced significantly greater improvements in skin texture and hydration than microneedling alone, with VISIA imaging confirming superior outcomes across all measured parameters in the growth factor group
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