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2), such as ion imbalance (pyroptosis), pH dysregulation (alkaliptosis), ATP depletion (parthanathos), generation of reactive oxygen species (parthanathos, pyroptosis, mitochondrial permeability transition), redox imbalance (ferroptosis), metals overload (ferroptosis, cuproptosis), lipid peroxidation (ferroptosis), nitrogen species formation (parthanatos), hypoxia (parthanatos) and exposure to various drugs, chemical compounds or radiation [4, 10]
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While most people obtain B-12 from meat, eggs, and dairy, excessive intake from food and supplements has no adverse effects in healthy individuals